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Toxicological Review of Bentazon

By Environmental Protection Agency

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Book Id: WPLBN0000020703
Format Type: PDF eBook:
File Size: 0.2 MB
Reproduction Date: 2007

Title: Toxicological Review of Bentazon  
Author: Environmental Protection Agency
Volume:
Language: English
Subject: Ecology, Natural resource issues, Environemtal protection
Collections: Environmental Awareness Library Collection
Historic
Publication Date:
Publisher: United States Environmental Protection Agency

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Protection Agency, B. E. (n.d.). Toxicological Review of Bentazon. Retrieved from http://www.gutenberg.cc/


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Excerpt: TOXICOLOGICAL REVIEW of BENTAZON

Table of Contents
TABLE OF CONTENTS FOREWORD ................................................................v AUTHORS, CONTRIBUTORS, AND REVIEWERS ................................ vi 1. INTRODUCTION...........................................................1 2. CHEMICAL AND PHYSICAL INFORMATION RELEVANT TO ASSESSMENTS ...........................................................2 3. TOXICOKINETICS RELEVANT TO ASSESSMENTS ............................2 3.1. ABSORPTION.........................................................2 3.2. DISTRIBUTION .......................................................3 3.3. METABOLISM ........................................................3 3.4. EXCRETION..........................................................3 4. HAZARD IDENTIFICATION .................................................3 4.1. STUDIES IN HUMANS .................................................3 4.2. SUBCHRONIC AND CHRONIC STUDIES AND CANCER BIOASSAYS IN ANIMALS ..............................................3 4.2.1. Subchronic Toxicity ...............................................3 4.2.2. Chronic Toxicity and Cancer Bioassay .................................5 4.3. REPRODUCTIVE/DEVELOPMENTAL STUDIES–ORAL ....................10 4.4. OTHER RELEVANT STUDIES..........................................11 4.4.1. Mutagenicity....................................................11 4.5. EVALUATION OF NONCANCER EFFECTS ..............................11 4.6. WEIGHT-OF-EVIDENCE EVALUATION AND CANCER CHARACTERIZATION ................................................12 4.7. SUSCEPTIBLE POPULATIONS .........................................12 4.7.1. Possible Childhood Susceptibility....................................12 4.7.2. Possible Gender Differences ........................................12 5. ORAL DOSE-RESPONSE ASSESSMENT .....................................13 5.1.ORAL REFERENCE DOSE (RfD) ........................................13 5.1.1. Choice of Principal Study and Critical Effect ............................13 5.1.2. Methods of Analysis ...............................................14 5.1.3. RfD Derivation ...................................................14 5.2.INHALATION REFERENCE CONCENTRATION (RfC) .....................15 5.3.CANCER ASSESSMENT ...............................................15

 
 



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